Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

- Coutts, Shelagh B., Ankolekar, Sandeep, Camden, Marie-Christine, Campbell, Bruce C. V., Casaubon, Leanne K., Catanese, Luciana, Chatterjee, Kausik, Choi, Philip M. C., Clarke, Brian, Dowlatshahi, Dar, Ferrari, Julia, Field, Thalia S., Appireddy, Ramana, Ganesh, Aravind, Ghia, D, Goyal, M, Greisenegger, S, Halse, O, Horn, M, Hunter, G, Imoukhuede, O, Kelly, PJ, Kennedy, J, Arenillas, Juan F., Kenney, C, Kleinig, TJ, Krishnan, K, Lima, F, Mandzia, JL, Marko, M, Martins, SO, Medvedev, G, Menon, BK, Mishra, SM, Assis, Zarina, Molina, C, Moussaddy, A, Muir, KW, Parsons, MW, Penn, AMW, Pille, A, Pontes-Neto, OM, Roffe, C, Serena, J, Simister, R, Bailey, Peter, Singh, N, Spratt, Neil, Strbian, D, Tham, CH, Wiggam, MI, Williams, DJ, Willmot, MR, Wu, T, Yu, AYX, Zachariah, G, Barber, Philip A., Zafar, A, Zerna, C, Hill, MD, Salluzzi, M, Blenkin, N, Dueck, A, Doram, C, Zhang, Q, Ryckborst, K, Bohn, S, Bazan, Rodrigo, Collier, Q, Taylor, F, Lethebe, BC, Jambula, A, Sage, K, Toussaint, L, Save, S, Lee, J, Laham, N, Sultan, AA, Buck, Brian H., Deepak, A, Sitaram, A, Demchuk, AM, Lockey, A, Micielli, A, Wadhwa, A, Arabambi, B, Graham, B, Bogiatzi, C, Doshi, D, Butcher, Ken S., Chakraborty, D, Kim, D, Vasquez, D, Singh, D, Tse, D, Harrison, E, Smith, EE, Teleg, E, Klourfeld, E, Klein, G

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

- Shrine, Nick, Izquierdo, Abril G., Hobbs, Brian D., Foong, RE, Harris, SE, Taylor, A, Redmond, P, Cook, JP, Mahajan, A, Lind, L, Palviainen, T, Lehtimäki, T, Raitakari, OT, Moll, Matthew, Kaprio, J, Rantanen, T, Pietiläinen, KH, Cox, SR, Pennell, CE, Hall, GL, Gauderman, WJ, Brightling, C, Wilson, JF, Vasankari, T, Kim, Wonji, Laitinen, T, Salomaa, V, Mook-Kanamori, DO, Timpson, NJ, Zeggini, E, Dupuis, J, Hayward, C, Brumpton, B, Langenberg, C, Weiss, S, Tal-Singer, Ruth, Homuth, G, Schmidt, CO, Probst-Hensch, N, Jarvelin, M-R, Morrison, AC, Polasek, O, Rudan, I, Lee, J-H, Sayers, I, Rawlins, EL, Bakke, Per, Dudbridge, F, Silverman, EK, Strachan, DP, Walters, RG, Morris, AP, London, SJ, Cho, MH, Wain, LV, Hall, IP, Tobin, MD, Fawcett, Katherine A., John, Catherine, Coley, Kayesha, Piga, Noemi Nicole, Pozarickij, Alfred, Chen, Jing, Wang, Carol A., Pennell, Craig E., Chen, Z, Li, L, China Kadoorie Biobank Collaborative Group,, Wijnant, SRA, Lahousse, L, Brusselle, G, Uitterlinden, AG, Manichaikul, A, Packer, Richard, Oelsner, EC, Rich, SS, Barr, RG, Kerr, SM, Vitart, V, Brown, MR, Wielscher, M, Imboden, M, Jeong, A, Bartz, TM, Hall, Robert J., Gharib, SA, Flexeder, C, Karrasch, S, Gieger, C, Peters, A, Stubbe, B, Hu, X, Ortega, VE, Meyers, DA, Bleecker, ER, Guyatt, Anna L., Gabriel, SB, Gupta, N, Smith, AV, Luan, J, Zhao, J-H, Hansen, AF, Langhammer, A, Willer, C, Bhatta, L, Porteous, D, Batini, Chiara, Smith, BH, Campbell, A, Sofer, T, Lee, J, Daviglus, ML, Yu, B, Lim, E, Xu, H, O'Connor, GT, Thareja, G, Thompson, Rebecca J., Albagha, OME, Qatar Genome Program Research (QGPR) Consortium,, Suhre, K, Granell, R, Faquih, TO, Hiemstra, PS, Slats, AM, Mullin, BH, Hui, J, James, A, Pavuluri, Chandan, Beilby, J, Patasova, K, Hysi, P, Koskela, JT, Wyss, AB, Jin, J, Sikdar, S, Lee, M, May-Wilson, S, Pirastu, N, Malik, Vidhi, Kentistou, KA, Joshi, PK, Timmers, PRHJ, Williams, AT, Free, RC, Wang, X, Morrison, JL, Gilliland, FD, Wang, CA

Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis

- Baldwin, Helen, Radua, Joaquim, Baeza, Inmaculada, Bartholomeusz, Cali F., Chee, Michael W. L., Colibazzi, Tiziano, Cooper, Rebecca E., Corcoran, Cheryl M., Cropley, Vanessa L., Ebdrup, Bjørn H., Fortea, Adriana, Glenthøj, Louise Birkedal, Antoniades, Mathilde, Hamilton, Holly K., Haut, KM, Hayes, RA, He, Y, Heekeren, K, Kaess, M, Kasai, K, Katagiri, N, Kim, M, Kindler, J, Haas, Shalaila S., Klaunig, MJ, Koike, S, Koppel, A, Kristensen, TD, Bin Kwak, Y, Kwon, JS, Lawrie, SM, Lebedeva, I, Lee, J, Lin, A, Frangou, Sophia, Loewy, RL, Mathalon, DH, Michel, C, Mizrahi, R, Moller, P, Nelson, B, Nemoto, T, Nordholm, D, Omelchenko, MA, Pantelis, C, Agartz, Ingrid, Raghava, JM, Rossberg, J, Roessler, W, Salisbury, DF, Sasabayashi, D, Schall, Ulrich, Smigielski, L, Sugranyes, G, Suzuki, M, Takahashi, T, Allen, Paul, Tamnes, CK, Tang, J, Theodoridou, A, Thomopoulos, S, Tomyshev, AS, Uhlhaas, PJ, Vaernes, TG, van Amelsvoort, TAMJ, Van Erp, TGM, Waltz, JA, Andreassen, Ole A., Westlye, LT, Wood, SJ, Zhou, JH, McGuire, P, Thompson, PM, Jalbrzikowski, M, Hernaus, D, Fusar-Poli, P, Rasser, Paul E., Atkinson, Kimberley, Bachman, Peter

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

- Blokland, Gabriëlla A. M., Grove, Jakob, Periyasamy, Sathish, Knowles, JA, Perlis, RH, Lucae, S, Boomsma, DI, Penninx, BWJH, Hottenga, J-J, de Geus, EJC, Willemsen, G, Milaneschi, Y, Tiemeier, H, Cairns, Murray J., Grabe, HJ, Teumer, A, Van der Auwera, S, Völker, U, Hamilton, SP, Magnusson, PKE, Viktorin, A, Mehta, D, Mullins, N, Adams, MJ, Tooney, Paul A., Breen, G, McIntosh, AM, Lewis, CM, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, iPSYCH, Hougaard, DM, Nordentoft, M, Mors, O, Mortensen, PB, Werge, T, Wu, Jing Qin, Als, TD, Børglum, AD, Petryshen, TL, Smoller, JW, Goldstein, JM, Kelly, Brian, Kirov, George, Sullivan, Patrick F., Corvin, Aiden, Riley, Brien P., Esko, Tõnu, Chen, Chia-Yen, Milani, Lili, Jönsson, EG, Palotie, A, Ehrenreich, H, Begemann, M, Steixner-Kumar, A, Sham, PC, Iwata, N, Weinberger, DR, Gejman, PV, Cotsapas, Chris, Sanders, AR, Buxbaum, JD, Rujescu, D, Giegling, I, Konte, B, Hartmann, AM, Bramon, E, Murray, RM, Pato, MT, Lee, J, Tobet, Stuart, Melle, I, Molden, E, Ophoff, RA, McQuillin, A, Bass, NJ, Adolfsson, R, Malhotra, AK, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Martin, NG, Fullerton, JM, Handa, Robert, Mitchell, PB, Schofield, PR, Forstner, AJ, Degenhardt, F, Schaupp, S, Comes, AL, Kogevinas, M, Guzman-Parra, J, Reif, A, Streit, F, Sirignano, L, Cichon, S, Grigoroiu-Serbanescu, M, Hauser, J, Lissowska, J, Mayoral, F, Müller-Myhsok, B, Świątkowska, B, Schulze, TG, Nöthen, MM, St Clair, David, Rietschel, M, Kelsoe, J, Leboyer, M, Jamain, S, Etain, B, Bellivier, F, Vincent, JB, Alda, M, O'Donovan, C, Cervantes, P, Lencz, Todd, Biernacka, JM, Frye, M, McElroy, SL, Scott, LJ, Stahl, EA, Landén, M, Hamshere, ML, Smeland, OB, Djurovic, S, Vaaler, AE, Mowry, Bryan J., Andreassen, OA, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Baune, BT, Air, T, Preisig, M, Uher, R, Levinson, DF, Weissman, MM, Potash, JB, Shi, J

Association of Structural Magnetic Resonance Imaging Measures with Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

- Jalbrzikowski, Maria, Hayes, Rebecca A., Mathalon, Daniel H., Suzuki, M, Theodoridou, A, Tomyshev, AS, Tor, J, Vaernes, TG, Velakoulis, D, Venegoni, GD, Vinogradov, S, Wenneberg, C, Westlye, LT, Katagiri, Naoyuki, Yamasue, H, Yuan, L, Yung, AR, van Amelsvoort, TAMJ, Turner, JA, van Erp, TGM, Thompson, PM, Hernaus, D, Hooker, Christine I., Smigielski, Lukasz, Colibazzi, Tiziano, Via, Esther, Tang, Jinsong, Koike, Shinsuke, Rasser, Paul E., Michel, Chantal, Wood, Stephen J., Lebedeva, Irina, Hegelstad, WTV, de la Fuente-Sandoval, C, Waltz, JA, Mizrahi, R, Corcoran, CM, Resch, F, Tamnes, CK, Haas, SS, Lemmers-Jansen, ILJ, Nordholm, Dorte, Agartz, I, Allen, P, Amminger, GP, Andreassen, OA, Atkinson, K, Bachman, P, Baeza, I, Baldwin, H, Bartholomeusz, CF, Borgwardt, S, Zhou, Juan H., Catalano, S, Chee, MWL, Chen, X, Cho, KIK, Cooper, RE, Cropley, VL, Dolz, M, Ebdrup, BH, Fortea, A, Glenthoj, LB, Fusar-Poli, Paolo, Glenthoj, BY, de Haan, L, Hamilton, HK, Harris, MA, Haut, KM, He, Y, Heekeren, K, Heinz, A, Hubl, D, Hwang, WJ, Uhlhaas, Peter J., Kaess, M, Kasai, K, Kim, M, Kindler, J, Klaunig, MJ, Koppel, A, Kristensen, TD, Kwon, JS, Lawrie, SM, Lee, J, Takahashi, Tsutomu, Leon-Ortiz, P, Lin, A, Loewy, RL, Ma, X, McGorry, P, McGuire, P, Mizuno, M, Moller, P, Moncada-Habib, T, Munoz-Samons, D, Sugranyes, Gisela, Nelson, B, Nemoto, T, Nordentoft, M, Omelchenko, MA, Oppedal, K, Ouyang, L, Pantelis, C, Pariente, JC, Raghava, JM, Reyes-Madrigal, F, Kwak, Yoo Bin, Roach, BJ, Rossberg, JI, Rossler, W, Salisbury, DF, Sasabayashi, D, Schall, Ulrich, Schiffman, J, Schlagenhauf, F, Schmidt, A, Sorensen, ME

Mepolizumab and Oral Corticosteroid Stewardship: Data from the Australian Mepolizumab Registry

- Thomas, Dennis, Harvey, Erin S., Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Langton, David, Baraket, Melissa, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Farah, Claude S., McDonald, Vanessa M., Wark, Peter A. B., Gibson, Peter G., Katsoulotos, GP, Lee, J, Radhakrishna, N, Reddel, HK, Rimmer, J, Sivakumaran, P, Wark, PAB, Gibson, PG, Stevens, Sean, Upham, John W., Katelaris, Constance H., Kritikos, Vicky, Gillman, Andrew, Harrington, John, Hew, Mark

The power of genetic diversity in genome-wide association studies of lipids

- Graham, Sarah E., Clarke, Shoa L., Locke, Adam E., Mollehave, LT, Thuesen, BH, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Marouli, Eirini, Scholz, M, Galesloot, TE, Bradfield, JP, Daw, EW, Zmuda, JM, Mitchell, JS, Fuchsberger, C, Christensen, H, Brody, JA, Feitosa, MF, Hwang, Mi Yeong, Wojczynski, MK, Preuss, M, Mangino, M, Christofidou, P, Verweij, N, Benjamins, JW, Engmann, J, Kember, RL, Slieker, RC, Lo, KS, Han, Sohee, Zilhao, NR, Phuong, L, Kleber, ME, Delgado, GE, Huo, S, Ikeda, DD, Iha, H, Yang, J, Liu, J, Leonard, HL, Narita, Akira, Marten, J, Schmidt, B, Arendt, M, Smyth, LJ, Canadas-Garre, M, Wang, Carol A., Nakatochi, M, Wong, A, Hutri-Kahonen, N, Sim, X, Choudhury, Ananyo, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, JC, Lyssenko, V, Ahmed, M, Jackson, AU, Irvin, MR, Oldmeadow, Chris, Kim, H-N, Ryu, S, Bentley, Amy R., Timmers, PRHJ, Arbeeva, L, Dorajoo, R, Lange, LA, Chai, X, Prasad, G, Lores-Motta, L, Pauper, M, Long, J, Li, X, Ekoru, Kenneth, Theusch, E, Takeuchi, F, Spracklen, CN, Loukola, A, Bollepalli, S, Warner, SC, Wang, YX, Wei, WB, Nutile, T, Ruggiero, D, Verma, Anurag, Sung, YJ, Hung, Y-J, Chen, S, Liu, F, Kentistou, KA, Gorski, M, Brumat, M, Meidtner, K, Bielak, LF, Trivedi, Bhavi, Smith, JA, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Xue, C, Zhang, J, Concas, MP, Vaccargiu, S, van der Most, PJ, Wu, Kuan-Han H., Martin, HC, Pitkanen, N, Cade, BE, Lee, J, van Der Laan, SW, Chitrala, KN, Weiss, S, Zimmermann, ME, Lee, JY, Choi, HS, Nethander, M, Hunt, KA, Freitag-Wolf, S, Southam, L, Rayner, NW, Wang, CA, Lin, S-Y, Wang, J-S, Couture, C, Lyytikainen, L-P, Nikus, K, Cuellar-Partida, G, Hui, Q, Vestergaard, H, Hildalgo, B, Giannakopoulou, O, Cai, Q, Obura, MO, van Setten, J, Schwander, K, Terzikhan, N, Shin, JH, Klarin, D, Jackson, RD, Reiner, AP, Martin, LW, Chen, Z, Li, L, Highland, HM, Young, KL, Kawaguchi, T, Thiery, J, Bis, JC, Zhu, X, Nadkarni, GN, Launer, LJ, Li, H, Nalls, MA, Raitakari, OT, Ichihara, S, Wild, SH, Nelson, CP, Campbell, H, Jager, S, Thorleifsson, G, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, PS, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, Bhatti, F, de Kleijn, D, Helgadottir, A, de Borst, GJ, Kim, EK, Adams, HHH, Ikram, MA, Asselbergs, FW, Kraaijeveld, AO, Beulens, JWJ, Shu, X-O, Rallidis, LS, Gudbjartsson, DF, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, AW, Kahonen, M, Perusse, L, Bouchard, C, Tonjes, A, Chen, Y-DI, Pennell, Craig E., Holm, H, Mori, TA, Lieb, W, Franke, A, Ohlsson, C, Mellstrom, D, Cho, YS, Lee, H, Yuan, J-M, Koh, W-P, Rhee, SY, Olafsson, I, Woo, J-T, Heid, IM, Stark, KJ, Volzke, H, Homuth, G, Evans, MK, Zonderman, AB, Polasek, O, Pasterkamp, G, Hoefer, IE, Kanoni, Stavroula, Akiyama, M, Redline, S, Pahkala, K, Oldehinkel, AJ, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Chen, YE, Bandinelli, S, Dedoussis, G, Sakaue, S, Thanaraj, TA, Kardia, SLR, Kato, N, Schulze, MB, Girotto, G, Jung, B, Boger, CA, Joshi, PK, Bennett, DA, De Jager, PL, Terao, C, Lu, X, Mamakou, V, Brown, M, Caulfield, MJ, Munroe, PB, Guo, X, Ciullo, M, Jonas, JB, Samani, NJ, Kaprio, J, Kanai, M, Pajukanta, P, Adair, LS, Bechayda, SA, de Silva, HJ, Wickremasinghe, AR, Krauss, RM, Wu, J-Y, Zheng, W, den Hollander, A, Bharadwaj, D, Zhou, W, Correa, A, Wilson, JG, Lind, L, Heng, C-K, Nelson, AE, Golightly, YM, Wilson, JF, Penninx, B, Kim, H-L, Attia, John, Brumpton, BM, Scott, Rodney J., Rao, DC, Arnett, DK, Walker, M, Koistinen, HA, Chandak, GR, Yajnik, CS, Mercader, JM, Tusie-Luna, T, Aguilar-Salinas, CA, Rasheed, H, Villalpando, CG, Orozco, L, Fornage, M, Tai, ES, van Dam, RM, Lehtimaki, T, Chaturvedi, N, Yokota, M, Reilly, DF, Ruotsalainen, SE, McKnight, AJ, Kee, F, Jockel, K-H, McCarthy, M, Palmer, CNA, Vitart, V, Hayward, C, Simonsick, E, van Duijn, CM, Lu, F, Havulinna, AS, Qu, J, Hishigaki, H, Lin, X, Marz, W, Parra, EJ, Cruz, M, Gudnason, V, Tardif, J-C, Lettre, G, 't Hart, LM, Veturi, Y, Elders, PJM, Damrauer, SM, Kumari, M, Kivimaki, M, van der Harst, P, Spector, TD, Loos, RJF, Province, MA, Psaty, BM, Brandslund, I, Zajac, Greg J. 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Inferring structural variant cancer cell fraction

- Cmero, Marek, Yuan, Ke, Cao, Shaolong, Scarlett, Christopher J., Christie, Elizabeth L., Cun, Yupeng, Dawson, Kevin J., Demeulemeester, Jonas, Dentro, Stefan C., Deshwar, Amit G., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Ong, Cheng Soon, Fan, Y, Fittall, MW, Garsed, DW, Gerstung, M, Getz, G, Gonzalez, S, Ha, G, Haase, K, Imielinski, M, Jerman, L, Schröder, Jan, Ji, Y, Jolly, C, Kleinheinz, K, Lee, J, Lee-Six, H, Leshchiner, I, Livitz, D, Malikic, S, Martincorena, I, Mitchell, TJ, Adams, David J., Morris, QD, Mustonen, V, Oesper, L, Peifer, M, Peto, M, Raphael, BJ, Rosebrock, D, Rubanova, Y, Sahinalp, SC, Salcedo, A, Anur, Pavana, Schlesner, M, Schumacher, SE, Sengupta, S, Shi, R, Shin, SJ, Spellman, PT, Spiro, O, Stein, LD, Tarabichi, M, Van Loo, P, Beroukhim, Rameen, Vembu, S, Vázquez-García, I, Wang, W, Wedge, DC, Wheeler, DA, Wintersinger, JA, Yang, TP, Yao, X, Yu, K, Zhu, H, Boutros, Paul C., Corcoran, NM, Papenfuss, T, Hovens, CM, Markowetz, F, Macintyre, G, Aaltonen, LA, Abascal, F, Abeshouse, A, Aburatani, H, Adams, DJ, Bowtell, David D. L., Agrawal, N, Ahn, KS, Ahn, SM, Aikata, H, Akbani, R, Akdemir, KC, Al-Ahmadie, H, Al-Sedairy, ST, Al-Shahrour, F, Alawi, M, Campbell, Peter J., Albert, M, Aldape, K, Alexandrov, LB, Ally, A, Alsop, K, Alvarez, EG, Amary, F, Amin, SB, Aminou, B, Ammerpohl, O